Genes and Proteins
NCBI
http://www.ncbi.nlm.nih.gov/
"Established in 1988 as a national resource for molecular biology information, NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information - all for the better understanding of molecular processes affecting human health and disease."
The NCBI website is an essential resource for bioinformaticians. It hosts a multitude of commonly-used tools including PubMed (a biomedical literature search engine), Entrez (a multiple-database search), and BLAST (a sequence alignment program).
Protein Data Bank (PDB)
http://www.rcsb.org/pdb/home/home.do
"The RCSB PDB provides a variety of tools and resources for studying the structures of biological macromolecules and their relationships to sequence, function, and disease."
The Protein Data Bank is a widely-used resource that provides 3-dimensional models of protein and nucleic acid structure. As of August 2008 there are over 50,000 structures available in the PDB website.
Gene Ontology
http://www.geneontology.org/
"The Gene Ontology (GO) project is a collaborative effort to address the need for consistent descriptions of gene products in different databases. The GO collaborators are developing three structured, controlled vocabularies (ontologies) that describe gene products in terms of their associated biological processes, cellular components and molecular functions in a species-independent manner. There are three separate aspects to this effort: first, we write and maintain the ontologies themselves; second, we make cross-links between the ontologies and the genes and gene products in the collaborating databases, and third, we develop tools that facilitate the creation, maintainence and use of ontologies.
KEGG (Kyoto Encyclopedia of Genes and Genomes)
http://www.genome.jp/kegg/
"KEGG is a database of biological systems, consisting of genetic building blocks of genes and proteins (KEGG GENES), chemical building blocks of both endogenous and exogenous substances (KEGG LIGAND), molecular wiring diagrams of interaction and reaction networks (KEGG PATHWAY), and hierarchies and relationships of various biological objects (KEGG BRITE). KEGG provides a reference knowledge base for linking genomes to biological systems and also to environments by the processes of PATHWAY mapping and BRITE mapping."
Biodiversity Informatics
GBIF (Global Biodiversity Information Facility)
http://www.gbif.org/
"GBIF is a global network of data providers that builds biodiversity information infrastructure and promotes the growth of biodiversity information content on the Internet by working with partner initiatives and coordinating activities worldwide."
In addition to work on biodiversity information infrastructure, GBIF provides global distribution data on the world's known species.
TDWG
http://www.tdwg.org/
"Biodiversity Information Standards (TDWG) is an international not-for-profit group that develops standards and protocols for sharing biodiversity data."
Encyclopedia of Life
http://www.eol.org/
"Comprehensive, collaborative, ever-growing, and personalized, the Encyclopedia of Life is an ecosystem of websites that makes all key information about all life on Earth accessible to anyone, anywhere in the world."
Other Bioinformatics Resource Lists
Association of College and Research Libraries, Bioinformatics Internet Resources
European Bioinformatics Institute
Bioinformatics Career Resources
bioinformatics.org jobs forum
BioPlanet.com
BioSpace.com
Biohealthmatics.com
Bioinformatics Journal
UIUC Student Resources
Illinois Informatics Institute
Bioinformatics Job board
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